Gillespie High School is a public high school in Gillespie, Illinois, which draws students from central Macoupin county. It competes in Class A, the "small school" division of the Illinois High School Association's (IHSA) State Championship Series.
Gillespie plays in the South Central Conference in all IHSA affiliated activities. The scholastic bowl team also competes in the South Central Scholastic League during the "fall" season.
The Miners are coached by Jarrod Herron.