The 2022 ACF Nationals was hosted by ACF at Minnesota.
It was head-edited by John Lawrence and edited by Will Alston, Stephen Eltinge, Stephen Liu, Eric Mukherjee, and Adam Silverman.
Georgia Tech A, led by Matt Bollinger, won in the first game of an advantaged final against a Stanford team that had won ICT the previous week. After an unprecedented four-way tie for third place was played off in a two-game, single elimination series, Ohio State placed third over WUSTL.
Yale won the Division I Undergraduate title over Brown in the second game of an advantaged final. House team Minnesota B took the Division II championship.
- Prior to this event, Georgia Tech had previously won ACF Nationals in 1996 and had not finished in the top 4 since 1997.
- At 51 teams, this is the largest ACF Nationals held to date; teams qualified to attend using the typical A-Value method for the first time since 2019. The field was originally set at 54 teams, but last-minute flight cancellations prevented three teams (MIT A, MIT B, and Columbia C) from attending. Teams were re-seeded to account for these field changes the night before the tournament, with revised seeds released at 6 AM morning-of.
- The tournament used digital scoresheets designed by Jeffrey Hill and Kyle Hill of MOQBA. Harry White created a webpage with live stats that updated in real time as scorekeepers filled out their sheets; that page is available here.
- Minnesota was the intended site of the never-held 2020 ACF Nationals.
- Chris Ray set a record at this tournament by winning a 9th career ACF Nationals all-star award, after previously tying Andrew Yaphe's mark of 8. Matt Bollinger became the second person to lead ACF Nationals in scoring for two different schools, after Yaphe did so for three, as well as the sixth person after Alice Chou, Seth Teitler, John Lawrence, Kevin Koai, and Yaphe (who did it for three) to win ACF Nationals titles for two different schools.
- The tournament awarded book prizes to the top 12 individual scorers, up from the top 8 at many previous instances of Nationals. These awards were given out after the prelim rounds, during the play-in matches for making top bracket, so several all-stars involved in those matches had to get their books later in the event.
- WUSTL became the 25th school all-time to finish in the top four at ACF Nationals, the first school from Missouri to do so, and the second member of the University Athletic Association to do so, after Chicago, which has finished in the top four 18 times.